Christina Toft
Panomics and Evolutionary Systems Microbiology (I2SYSBIO) · I2SYSBIO
Biography
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Dr. Christina Toft is a tenured researcher at the Spanish National Research Council (CSIC) and leads a research group at the Institute for Integrative Systems Biology (I2SysBio). She holds a BSc in Computational Biology and Bioinformatics from the National University of Ireland, Maynooth, where she received two Gold Medals, and a PhD from Trinity College Dublin, where she investigated genomic adaptations in endosymbiotic bacteria. Her postdoctoral work includes studies on the evolution of Bartonella at Uppsala University and on yeast hybridization and evolutionary mechanisms in the Saccharomycetaceae family at the University of Valencia, supported by EMBO and JdC fellowships. |
Profile
| Institution | I2SYSBIO |
| Position | Tenured Researcher, CSIC |
| Home page | https://i2sysbio.es/investigator/58/ |
| Contact email | Christina.Toft@csic.es |
| ORCID | 0000-0003-1714-6703 |
BCB Hub
| BCB Committee | Support BCB Excellence |
| BCB Tools | GWideCodeML |
| BCB Services |
Research
Research topics
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Research lines
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Projects, networks, transfer & teaching
Funded projects 2
Publications 27 entries
- Evolution of virulence of a plant RNA virus in developmental stage-structured host populations Article · 31 Aug 2026
- Chronic infection ofCaenorhabditis elegansby Orsay virus induces age-dependent immunity and superinfection exclusion Preprint · 26 Dec 2024
- Mapping the mutational landscape of a full viral proteome reveals distinct profiles of mutation tolerability Preprint · 7 Mar 2024
- The Role of Ancestral Duplicated Genes in Adaptation to Growth on Lactate, a Non-Fermentable Carbon Source for the Yeast Saccharomyces cerevisiae Article · 14 Nov 2021
- GWideCodeML: A Python Package for Testing Evolutionary Hypotheses at the Genome-Wide Level Software · 1 Dec 2020
View all (22 more)
- Transcriptional Rewiring, Adaptation, and the Role of Gene Duplication in the Metabolism of Ethanol of Saccharomyces cerevisiae Article · 25 Aug 2020
- Evolution from Free-Living Bacteria to Endosymbionts of Insects: Genomic Changes and the Importance of the Chaperonin GroEL Book / chapter · 2020
- RNAseq-based transcriptome comparison of Saccharomyces cerevisiae strains isolated from diverse fermentative environments Article · Sep 2017
- Expression properties exhibit correlated patterns with the fate of duplicated genes, their divergence, and transcriptional plasticity in Saccharomycotina. Article · 15 Jun 2017
- Genome Mutational and Transcriptional Hotspots Are Traps for Duplicated Genes and Sources of Adaptations Article · May 2017
- Chance and necessity in the genome evolution of endosymbiotic bacteria of insects Article · 21 Mar 2017
- The Phenotypic Plasticity of Duplicated Genes in Saccharomyces cerevisiae and the Origin of Adaptations Article · 1 Jan 2017
- Essentiality Is a Strong Determinant of Protein Rates of Evolution during Mutation Accumulation Experiments in Escherichia coli Article · 25 Aug 2016
- Preservation of genetic and regulatory robustness in ancient gene duplicates of Saccharomyces cerevisiae Article · 22 Aug 2014
- A Gene Transfer Agent and a Dynamic Repertoire of Secretion Systems Hold the Keys to the Explosive Radiation of the Emerging Pathogen Bartonella Article · 28 Mar 2013
- The Roles of Whole-Genome and Small-Scale Duplications in the Functional Specialization of Saccharomyces cerevisiae Genes Article · 3 Jan 2013
- Proteome-Wide Analysis of Functional Divergence in Bacteria: Exploring a Host of Ecological Adaptations Article · 26 Apr 2012
- Evolutionary microbial genomics: insights into bacterial host adaptation Article · 2 Jun 2010
- Structural calibration of the rates of amino acid evolution in a search for Darwin in drifting biological systems Article · 13 May 2010
- Two chaperonin systems in bacterial genomes with distinct ecological roles Article · Feb 2010
- Phylogenomic inference of functional divergence Article · Oct 2009
- Genome-Wide Functional Divergence after the Symbiosis of Proteobacteria with Insects Unraveled through a Novel Computational Approach Article · 3 Apr 2009
- Computational biology methods and their application to the comparative genomics of endocellular symbiotic bacteria of insects Article · 11 Mar 2009
- Selection for translational robustness in Buchnera aphidicola, endosymbiotic bacteria of aphids Article · 6 Jan 2009
- Molecular Coevolution and the Three-Dimensionality of Natural Selection Book / chapter · 2009
- The evolution of the flagellar assembly pathway in endosymbiotic bacterial genomes Article · 23 Jun 2008
- GRAST: a new way of genome reduction analysis using comparative genomics Article · 6 Apr 2006
