Detalle de: Bioinformatics, Computational Biology and Data Science
| Title | Bioinformatics, Computational Biology and Data Science |
| Description |
[EN] The Bioinformatics, Computational Biology and Data Science (BioCoDas) group comprises research staff dedicated to compiling, organising, exploring, and evaluating data generated from scientific investigations to look for patterns and generate new knowledge in agri-food research. Due to its multidisciplinary nature, the research carried out by the group stands out for its transversal capacity, being applicable to the multiple lines of research developed at the Institute of Agrochemistry and Food Technology (IATA-CSIC). The group's scientific activity is circumscribed, but not limited, to the following fields of investigation: biomedicine, human nutrition, agri-food production systems, bibliometrics, open science, materials revaluation, and the circular economy, among others. [ES] El grupo de Bioinformática, Biología Computacional y Ciencia de Datos está formado por cuatro investigadores consolidados que trabajan activamente en aspectos fundamentales de la ciencia de los alimentos, como la generación, el procesamiento, el análisis y integración de datos multivariados y multiómicos procedentes de sistemas agroalimentarios y de matrices alimentarias, así como de muestras animales, humanas y ambientales. Para ello, el grupo desarrolla y aplica métodos bioinformáticos, estadísticos y de ciencia de datos que permiten estudiar sistemas biológicos complejos y extraer conocimiento relevante a partir de grandes volúmenes de información. Estos métodos se aplican al estudio de la composición, función y dinámica de sistemas biológicos y microbianos, a la identificación de mecanismos moleculares, biomarcadores y patrones predictivos, y al desarrollo de protocolos, herramientas computacionales, flujos de trabajo reproducibles y modelos basados en aprendizaje automático, estadística avanzada e inteligencia artificial. La estandarización, armonización, almacenamiento, gestión, reutilización y difusión de dichos datos también forman parte activa de la investigación que realizan los investigadores del grupo; por lo tanto, nuestras tareas implican un compromiso directo con las políticas de ciencia abierta, la reproducibilidad de la investigación y los principios FAIR. |
| Home Page | https://iata.csic.es/bioinformatica-biologia-computacional-y-ciencia-de-datos/ |
| Contact Email | abenitez@iata.csic.es |
| Collaborating Companies | Arla Food Agrifiber |
| Spin Off | |
| Patents | 1. (Patent) Authors: Sanz Y.; Benítez-Páez, A; Gómez del Pulgar, Eva Mª; Francés, R.; Gómez-Hurtado, I.; Piñero, Paula; Juanola, Oriol. Title: “Bifidobacterium longum sub. infantis strain and its use” Request No.: P201830961. Request date: 05-Oct-2018. Protection issue: PCT1641.1407 (04/Dec/2019). Institutional ownership: CSIC, FISABIO, UMH, CIBER, Spain. 2. (Patent) Authors: Sanz Y; López-Almela, I; Gómez del Pulgar, Eva Mª; Benítez-Páez, A; Romaní-Pérez, M. Title: “Phascolarctobacterium faecium for prevention and treatment of obesity and comorbidities” Request No.: P201831166. Request date: 30-Nov-2018. Request issue: PCT/ES2019/070821 (02/Dec/2019). Institutional ownership: CSIC, Spain. 3. (Patent) Authors: Sanz Y; López-Almela, I; Gómez del Pulgar, Eva Mª; Benítez-Páez, A; Romaní-Pérez, M. Title: “Bacteria Hodemanella sp. and its use” Request No.: P201831282. Request date: 26-Dec-2018. Request issue: PCT/ES2019/070882 (24/Dec/2019). Institutional ownership: CSIC, Spain. |
| Hpc Resources | Responsible of the HPC cluster at the IATA-CSIC. |
| Institution | IATA |
| Ontology | Omics, Computational Methods, Resources, Transcriptomics, RNA Sequencing (RNA-seq), Data Analysis, Artificial Intelligence, Machine Learning in Biology, Bioinformatics Software and Tools, Annotation tools, Analysis packages (R, Python, etc.), Data Visualization, Applications of Computational Biology, Model organisms, Bioinformatics enabling techniques, Standards in Computational Biology, Benchmarking, Genomics, Genome Sequencing, Genome Assembly, Large language models, Functional genomics, Functional annotation, Function prediction, Structural bioinformatics, Experimental structure determination, Molecular flexibility, Bioinformatics Infrastructure, Biological Databases, Expression Profiling, Computational models and simulations, Biosystems Modeling, Gene regulatory networks, Metabolic modelling, Computational Techniques, High-performance Computing, Parallel Computing, Desktop application, Personal medicine, Systems Biology, Genomic Annotation, Variant calling, Epigenomics, DNA methylation, 3D chromatin structure, Integrative Analysis, Regulatory biology, Containers Computing, Statistical Methods for Biology, Frequentist analysis, Web-service, Molecular evolution, Conservation Analysis, Data Repositories, FAIRfication, Bioinformatics education, Population genomics, Evolutionary modelling, Ecological modelling, Workflow managers, Sequence analysis, Sequence Alignment, Phylogenetic Analysis, Mutation Analysis and design, Chromatin accessibility, Proteomics, Experimental design, Mapping, Pathway analysis, Food safety, Biological Ontologies, Plant genomics, Metabolomics, Metabolome profiling, Multivariate statistics, Image analysis, Network Biology, Biomolecular simulation, Structure-function relationship, Drug Discovery and design, Evolutionary rates, Single-cell omics, Single-cell (scRNA-seq), Structure prediction, Molecular Interactions/Docking, Protein-Protein Interactions, Development, Bayesian statistics, Non-parametric statistics, Biological interpretation, Non-model organisms, Microbial communities, Metagenomics, Population dynamics, Text mining, Natural Language Processing (NLP), Deep Learning in Biology, Protein/Nucleic Acid design, Animal genomics, Cloud Computing, Amplicon Sequencing, Clinical data, Spatial transcriptomics, Green Computing, Sequence error correction, Behavioral Ecology, Phosphoproteomics, Metabolite annotation, Metabolite Biomarker Identification, Metatranscriptomics, Viromics, Structural genomics, Marine Systems, Knowledge graphs, Histone structure and regulation, Laboratory Information Management, Lipidomics |
| Tools | microSTASIS |
| Service Units | |
| Research Lines | Interacciones hospedador-microbiota, Diet-host-microbe interactions in health and disease |
| Funded Projects | Functional mimicry of the human dipeptidyl peptidase-4 activity by the gut microbes and dietary strategies for its inhibition – MIMICROBES, Identification of genetic and metabolic components of the gut microbiota and dietary strategies for preventing non-communicable diseases., Mimetismo funcional de la actividad dipeptidil peptidasa 4 por la microbiota intestinal humana y estrategias dietéticas para su inhibición |
| Selected Publications |
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| Researchers | Alfonso Benítez Páez, Raúl Cabrera Rubio |