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Detalle de: Poxvirus immunomodulatory proteins

Title Poxvirus immunomodulatory proteins
Description

Poxvirus proteins secreted from infected cells that interact with type I interferon, tumor necrosis factor or chemokines and modulate their activity, and a viral mechanism blocking DNA sensing (poxin/schlafen); their contribution to pathogenesis is tested in a mouse model of infection (mousepox), and the knowledge is used to develop new anti-inflammatory therapeutic approaches.

Research Groups Immunity and Viromics
Researchers Antonio Alcamí, Sergio Sánchez Carrillo

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