Javier Buceta
TheSiMBioSys (Theoretical and In Silico Modeling of Biological Systems) · I2SYSBIO
Associated Unit I2SYSBIO - CRM · I2SYSBIO
Biography
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I graduated in Physics (M.Sc. Theoretical Physics) in Madrid. In addition, I got a M.Sc. degree as Computer Analyst. During my Ph.D. thesis (Physics, Madrid), I researched on pattern formation, molecular motors, interfacial dynamics, and phase transitions using the Statistical Mechanics framework. Afterwards, I moved to the University of California San Diego (Dept. of Chem. and Biochem. and the Institute for Nonlinear Science) as a postdoc (Prof. Lindenberg’s group) and worked on different topics (pattern formation, disease spreading, tumor growth...). Later, I was awarded by La Jolla Interfaces in Science/Centre for Theoretical Biological Physics programme to conduct research on ‘Left-Right Symmetry Breaking in Embryo Development’ at Salk Institute for Biological Studies/UCSD (J.C. Izpisua-Belmonte/K. Lindenberg). In 2004 I moved to the Barcelona Science Park as a P.I. (“Ramón y Cajal” research fellow). I got tenured but in 2014 I accepted a position as Associate Professor at Lehigh University (PA, USA, Bioengineering Dpt. and Dpt. of Chemical and Biomolecular Engineering) where I was the founding D.T. & W.E. Schiesser Faculty Fellow. In 2020 I moved back to Spain to the Institute for Integrative Systems Biology (I2SysBio) at Valencia as a tenured scientist/P.I, where I am currently deputy director. Since 2022 I am member of the direction board of the Spanish Biophysical Society. |
Profile
| Institution | I2SYSBIO |
| Position | Group Leader/PI |
| Home page | http://www.thesimbiosys.com |
| Contact email | javier.buceta@csic.es |
| ORCID | 0000-0003-1791-0011 |
BCB Hub
| BCB Committee | Not a member |
| BCB Tools | TiFoSi, Bacteria Segmentation/Tracking Tool, ANISE |
| BCB Services |
Research
Research topics
Research lines
None
Projects, networks, transfer & teaching
Funded projects 3
- Cells2Spine: Spatial Transcriptomics and Cell Communication Models applied to tissue regeneration and treatment in Spinal Cord Injury with Precision Nanomedicine
- Conexión CSIC en Biología Computacional y Bioinformática (BCBHub)
- "ORIGIN AND IMPLICATIONS OF MIN AND ERK MECHANICAL WAVES IN THE GROWTH OF CELLS AND TISSUES"
Publications 80 entries
- Electrical stimulation and stem cell subdural implantation decrease microglia reactivity after spinal cord injury Article · Aug 2026
- The Tight Backbone Spread Model for Simulating 3D Epithelial Cell Layer Dynamics Article · 24 Jul 2026
- Genetic engineering of gut commensals: heterologous protein expression in Bifidobacterium animalis subsp. lactis CECT8145 Article · 2026
- The peroxiredoxin Tsa1 promotes stationary phase entry by suppressing PKA activity Preprint · 26 Nov 2025
- E. coli filament buckling modulates Min patterning and cell division Article · 8 Sep 2025
View all (75 more)
- 3DTubularVoronoi : a Voronoi-Based Framework for Estimating Equilibrium Cellular Packing in 3D Tubular Epithelia Preprint · 6 Sep 2025
- Spatial Dynamics and Emergent Properties of pLS20 Conjugation on Solid Surfaces Preprint · 4 Mar 2025
- Physical communication pathways in bacteria: an extra layer to quorum sensing Article · 4 Mar 2025
- Mechanical strain modulates Min patterning and division inE. colifilaments Preprint · 26 Feb 2025
- Apico-basal intercalations enable the integrity of curved epithelia Article · 1 Jan 2025
- Efficient Modeling of 3D Epithelial Cell Structure Dynamics via Backbone Spreads Conference paper · 2025
- Stochastic analysis of Ebola infection in small zoonotic niches Article · Nov 2024
- Comprehensive profiling of neutralizing polyclonal sera targeting coxsackievirus B3 Article · 12 Oct 2023
- Random field calibration with data on irregular grid for regional analyses: A case study on the bare carrying capacity of bats in Africa Article · Sep 2023
- Developmental Pattern Formation: Spanish Contributions from a Biophysical Perspective Article · 6 May 2023
- Estimation of Ebola’s spillover infection exposure in Sierra Leone based on sociodemographic and economic factors Article · 1 Sep 2022
- A quantitative biophysical principle to explain the 3D cellular connectivity in curved epithelia Article · Aug 2022
- Bacterial degrons in synthetic circuits Article · Aug 2022
- ANISE: an application to design mechanobiology simulations of planar epithelia Article · 20 Jul 2022
- Mechanics and self-organization in tissue development Article · Dec 2021
- The complex three-dimensional organization of epithelial tissues Article · 1 Jan 2021
- Mycobacterium Phage Butters-Encoded Proteins Contribute to Host Defense against Viral Attack Article · 27 Oct 2020
- Self-sustained planar intercalations due to mechanosignaling feedbacks lead to robust axis extension during morphogenesis Article · 3 Jul 2020
- TiFoSi: an efficient tool for mechanobiology simulations of epithelia Software · 26 Jun 2020
- Mechanical coordination is sufficient to promote tissue replacement during metamorphosis in Drosophila Article · 20 Dec 2019
- A non-linear analysis of Turing pattern formation Article · 9 Aug 2019
- Scutoids: Understanding the 3D Packing of Curved Epithelia Article · Feb 2019
- A Cell Segmentation/Tracking Tool Based on Machine Learning Software · 2019
- Erratum to: Scutoids are a geometrical solution to three-dimensional packing of epithelia (Nature Communications, (2018), 9, 1, (2960), 10.1038/s41467-018-05376-1) Article · 8 Oct 2018
- Scutoids are a geometrical solution to three-dimensional packing of epithelia Article · 27 Jul 2018
- A Markovian Approach towards Bacterial Size Control and Homeostasis in Anomalous Growth Processes Article · 25 Jun 2018
- A Predictive Spatial Distribution Framework for Filovirus-Infected Bats Article · 22 May 2018
- Differentiation of live and heat-killed E. coli by microwave impedance spectroscopy Article · Feb 2018
- Finite cell-size effects on protein variability in Turing patterned tissues Article · Aug 2017
- Modeling the Ebola zoonotic dynamics: Interplay between enviroclimatic factors and bat ecology Article · 12 Jun 2017
- Under Pressure: Mechanosensitivy Properties of the Bacterial Divisome Article · Feb 2017
- The cellular Ising model: A framework for phase transitions in multicellular environments Article · Jun 2016
- Stochastic stabilization of phenotypic States: the genetic bistable switch as a case study. Article · 11 Sep 2013
- Interplay of cytoskeletal activity and lipid phase stability in dynamic protein recruitment and clustering Article · 10 Sep 2013
- Sonic hedgehog signaling switches the mode of division in the developing nervous system Article · Aug 2013
- Dynamics of the quorum sensing switch: Stochastic and non-stationary effects Article · 2013
- Dynamics and mechanical stability of the developing dorsoventral organizer of the wing imaginal disc Article · 29 Sep 2011
- Noise regulation by quorum sensing in low mRNA copy number systems Article · 20 Jan 2011
- Direct mapping of nanoscale compositional connectivity on intact cell membranes Article · 16 Aug 2010
- Interplay between intrinsic noise and the stochasticity of the cell cycle in bacterial colonies Article · Jun 2010
- Pattern formation in nonequilibrium lipid membranes: From membrane undulations to lipid rafts Article · Mar 2010
- Noise-induced coherence in multicellular circadian clocks Article · May 2009
- A spatial toggle switch drives boundary formation in development Article · Dec 2008
- Phase separation in three-component lipid membranes: From Monte Carlo simulations to Ginzburg-Landau equations Article · 9 Jan 2008
- Robustness and stability of the gene regulatory network involved in DV boundary formation in the Drosophila wing Article · 11 Jul 2007
- Noise-induced oscillatory behavior in field-dependent relaxational dynamics Article · 19 Apr 2006
- Comprehensive study of pattern formation in relaxational systems Article · 8 Feb 2006
- Generation of dynamic structures in nonequilibrium reactive bilayers Article · 18 Nov 2005
- Nodal cilia dynamics and the specification of the left/right axis in early vertebrate embryo development Article · Oct 2005
- Erratum: Nonequilibrium patterns and shape fluctuations in reactive membranes (Physical Review E (2005) 71 (051906)) Article · 14 Sep 2005
- Nonequilibrium patterns and shape fluctuations in reactive membranes Article · 18 May 2005
- Comments on the article "The Universal Dynamics of Tumor Growth" A. Brú et al Article · May 2005
- Ratchets in homogeneous extended systems: Internal modes and the role of noise Article · Dec 2004
- Effects of internal fluctuations on the spreading of Hantavirus Article · Dec 2004
- Habitat size and extinction in population dynamics Conference paper · 25 May 2004
- Outbreaks of Hantavirus induced by seasonality Article · 26 Feb 2004
- Extinction in population dynamics Article · 26 Feb 2004
- Comprehensive study of phase transitions in relaxational systems with field-dependent coefficients Article · 15 Jan 2004
- Dynamics of two granules Article · 26 Aug 2003
- Spatial patterns induced purely by dichotomous disorder Article · 23 Jul 2003
- Patterns in reaction-diffusion systems generated by global alternation of dynamics Article · Jul 2003
- Dynamical scaling analysis of plant callus growth Article · Jul 2003
- Noise-driven mechanism for pattern formation Article · 27 Feb 2003
- Erratum: Pattern formation induced by nonequilibrium global alternation of dynamics (Physical Review E (2002) 66 (036216)) Article · 30 Dec 2002
- GLOBAL ALTERNATION-INDUCED PATTERNS Article · Dec 2002
- Switching-induced Turing instability Article · 4 Oct 2002
- Pattern formation induced by nonequilibrium global alternation of dynamics Article · 24 Sep 2002
- SPATIAL PATTERNS INDUCED BY RANDOM SWITCHING Article · Mar 2002
- Stationary and oscillatory spatial patterns induced by global periodic switching Article · 26 Dec 2001
- Random Ginzburg-Landau model revisited: Reentrant phase transitions Article · 20 Feb 2001
- Negative resistance and anomalous hysteresis in a collective molecular motor Article · 1 Jun 2000
- Finite resolution effects in the analysis of the scaling behavior of rough surfaces Article · 1 May 2000
- Small scale properties of the stochastic stabilized Kuramoto-Sivashinsky equation Article · Mar 1998
- The stochastic stabilized Kuramoto-Sivashinsky equation: A model for compact electrodeposition growth Article · Nov 1997
- Noise-induced spatial patterns Article · Feb 1996
