Alexandre Clop i Ponte
Animal genomics · CRAG
Biography
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Veterinarian by training with experience on genomics analysis of livestock species and human biomedical research. PhD at Universitat Autònoma de Barcelona. Two postdocs in animal and human genomics at the University of Liege and Kings' College London. 2.5 year experience in technology translation in the frame of animal genomics. Currently working at the Centre for Research in Agricultural Genomics CRAG, on Animal Genomics. My research expertise resides in the use of structural and functional genomics to decipher the catalogue of polymorphisms causing phenotypic variation in animals, including traits of economic interest in livestock breeding and human health. At present, most of my research focuses on whole genome sequencing and single cell multiomics (ATAC + RNA) to identify DNA variants with strong potential to affect male reproduction traits in pigs. |
Profile
| Institution | CRAG |
| Position | Researcher |
| Home page | https://www.linkedin.com/in/alex-clop-i-ponte-89ab2042/ |
| Contact email | alex.clop@cragenomica.es |
| ORCID | 0000-0001-9238-2728 |
BCB Hub
| BCB Committee | Not a member |
| BCB Tools | |
| BCB Services |
Research
Research topics
OmicsComputational MethodsTranscriptomicsRNA Sequencing (RNA-seq)Applications of Computational BiologyGenomicsSingle-cell omicsSingle-cell (scRNA-seq)Animal genomics
Research lines
Projects, networks, transfer & teaching
Research networks
International
- Member of the International Society of Animal Genomics ISAG
- Member of the Functional Annotation of Animal Genomes Consortium FAANG
- Member of the Societat Catalana de Biologia
Industry & knowledge transfer
Collaborating companies
- Pig Improvement Company PIC
- Gepork
- Semen Cardona
Teaching
Doctoral programs
- Doctoral Programme in Animal Production - Universitat Autònoma de Barcelona (affiliated professor - "Professor vinculat", Department of Animal and Food Sciences; invited position; since November 2013)
Funded projects 4
Publications 49 entries
- Genomic, transcriptomic and epigenomic analysis towards the understanding of porcine semen quality traits. Past, current and future trends Article · Oct 2024
- PigBiobank: a valuable resource for understanding genetic and biological mechanisms of diverse complex traits in pigs Article · 13 Nov 2023
- Integrating large-scale meta-GWAS and PigGTEx resources to decipher the genetic basis of complex traits in pig Preprint · 11 Oct 2023
- Micrococcal nuclease sequencing of porcine sperm suggests enriched co-location between retained histones and genomic regions related to semen quality and early embryo development Article · 21 Jun 2023
- A compendium of genetic regulatory effects across pig tissues Preprint · 25 Nov 2022
View all (44 more)
- Exploring the ovine sperm transcriptome by RNAseq techniques. I Effect of seasonal conditions on transcripts abundance Article · 14 Mar 2022
- Assessing the levels of intraspecific admixture and interspecific hybridization in Iberian wild goats ( Capra pyrenaica ) Article · 29 Sep 2021
- Characterization of the Impact of Density Gradient Centrifugation on the Profile of the Pig Sperm Transcriptome by RNA-Seq Article · 19 Jul 2021
- Micrococcal nuclease sequencing of porcine sperm suggests a nucleosomal involvement on semen quality and early embryo development Preprint · 31 Mar 2021
- A systems biology framework integrating GWAS and RNA-seq to shed light on the molecular basis of sperm quality in swine Article · Dec 2020
- Characterisation of sperm piRNAs and their correlation with semen quality traits in swine Article · 23 Nov 2020
- A pilot RNA-seq study in 40 pietrain ejaculates to characterize the porcine sperm microbiome Article · Nov 2020
- Whole genome sequencing identifies Allelic Ratio Distortion in sperm involving genes related to spermatogenesis in a swine model Article · 15 Sep 2020
- Identification of circular RNAs in porcine sperm and evaluation of their relation to sperm motility Article · 14 May 2020
- An integrative systems biology approach to identify the molecular basis of sperm quality in swine Preprint · 30 Mar 2020
- A RNA-seq characterization of the porcine sperm microbiome Preprint · 18 Mar 2020
- A RNA-Seq Analysis to Describe the Boar Sperm Transcriptome and Its Seasonal Changes Article · 16 Apr 2019
- A technical assessment of the porcine ejaculated spermatozoa for a sperm-specific RNA-seq analysis Article · 26 Apr 2018
- A targeted genotyping approach enhances identification of variants in taste receptor and appetite/reward genes of potential functional importance for obesity-related porcine traits Article · 14 Feb 2018
- Low mitochondrial diversity in native Italian pig breeds is consistent with the occurrence of strong population bottlenecks Article · 4 Sep 2017
- Mitochondrial DNA variation in Ukrainian wild boars Article · 30 Aug 2017
- Canine Leishmaniasis Progression is Associated with Vitamin D Deficiency Article · 13 Jun 2017
- A genome-wide association analysis for carcass traits in a commercial Duroc pig population Article · 3 Feb 2017
- Identification of genetic variation in the swine toll-like receptors and development of a porcine TLR genotyping array Article · 31 Mar 2016
- An In-Depth Characterization of the Major Psoriasis Susceptibility Locus Identifies Candidate Susceptibility Alleles within an HLA-C Enhancer Element Article · 19 Aug 2013
- Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis Article · 21 Aug 2012
- A Genome-Wide Association Study of Female Sexual Dysfunction Article · 11 Apr 2012
- Copy number variation in the genomes of domestic animals Article · 6 Mar 2012
- Allele-Specific Cytokine Responses at the HLA-C Locus: Implications for Psoriasis Article · Mar 2012
- A Systems Model for Immune Cell Interactions Unravels the Mechanism of Inflammation in Human Skin Article · 2 Dec 2010
- Characterization of OAR1 and OAR18 QTL associated with muscle depth in British commercial terminal sire sheep Article · 30 Sep 2010
- Identification of positively selected sites in the goat kappa casein (CSN3) gene Article · 6 May 2010
- Short communication: Genetic variability in the predicted microRNA target sites of caprine casein genes Article · Apr 2010
- Insights into the importance of miRNA-related polymorphisms to heart disease Article · Aug 2009
- Integrating Y-Chromosome, Mitochondrial, and Autosomal Data to Analyze the Origin of Pig Breeds Article · 17 Jun 2009
- Two single nucleotide polymorphisms in the myostatin (GDF8) gene have significant association with muscle depth of commercial Charollais sheep Article · 11 Jul 2008
- Differential expression of sarcoplasmic proteins in four heterogeneous ovine skeletal muscles Article · Jan 2007
- Proteomic analysis of ovine muscle hypertrophy Article · 1 Dec 2006
- A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep Article · 4 Jun 2006
- Polymorphic Polymorphic MicroRNA-Target Interactions: A Novel Source of Phenotypic Variation Article · 1 Jan 2006
- The value of prior information for detection of QTL affecting longitudinal traits: an example using Von Bertalanffy growth function Article · 27 Jan 2005
- Derivation of a Bayes Factor to Distinguish Between Linked or Pleiotropic Quantitative Trait Loci Article · Feb 2004
- Estimating the frequency of Asian cytochrome B haplotypes in standard European and local Spanish pig breeds Article · 15 Jan 2004
- Assignment of the mitochondrial glycerol‐3‐phosphate acyltransferase ( GPAT ) gene to porcine chromosome 14 Article · 18 Sep 2003
- Detection of QTL affecting fatty acid composition in the pig Article · 1 Sep 2003
- Quantitative trait locus mapping for meat quality traits in an Iberian × Landrace F2 pig population1 Article · 1 Nov 2002
- QTL mapping for growth and carcass traits in an Iberian by Landrace pig intercross: additive, dominant and epistatic effects Article · Oct 2002
- Test for positional candidate genes for body composition on pig chromosome 6 Article · 15 Jul 2002
- A QTL on pig chromosome 4 affects fatty acid metabolism: evidence from an Iberian by Landrace intercross. Article · 2000