Carolina Tafalla Piñeiro
Biography
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Carolina Tafalla is a Research Professor at the Animal Health Research Centre (CISA) of the National Institute for Agricultural and Food Research and Technology (INIA), in turn part of the Spanish National Research Council (CSIC). In 2000 she obtained her PhD in Biology from the University of Santiago de Compostela, after working for 3 years at the Instituto de Investigaciones Marinas of Vigo (IIM-CSIC), studying the antiviral immune response in fish. In 2002 she was awarded an individual Marie Curie fellowship for a stay at the Centre de Recherche de Jouy-en-Josas (INRA, France), focused on the molecular biology of fish rhabdoviruses. In 2003 she returned to Spain with a Ramón y Cajal contract and founded the Fish Immunology and Pathology Group at CISA, which she currently leads. |
Profile
| Institution | INIA |
| Position | Research Professor, Head of the Fish Immunology and Pathology Group |
| Home page | https://www.linkedin.com/in/carolina-tafalla-5070b067/ |
| Contact email | tafalla@inia.csic.es |
| ORCID | 0000-0002-0860-2976 |
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| BCB Committee | Not a member |
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Projects, networks, transfer & teaching
Industry & knowledge transfer
Patents
- 4 patents filed.
Funded projects 1
Publications 107 entries
- Dietary Methionine Supplementation Improves Rainbow Trout (Oncorhynchus mykiss) Immune Responses Against Viral Haemorrhagic Septicaemia Virus (VHSV) Article · 16 Jan 2026
- Unraveling the Systemic and Local Immune Response of Rainbow Trout (Oncorhynchus mykiss) to the Viral Hemorrhagic Septicemic Virus Article · 5 Aug 2025
- Teleost IgM+ plasma-like cells: beyond antibody secretion Article · 1 Jan 2025
- Pleiotropic Role of Rainbow Trout CXCRs in Response to Disease and Environment: Insights from Transcriptional Signatures and Structure Analysis Article · 12 Mar 2024
- Differential response of RTGUTGC and RTGILL‐W1 rainbow trout epithelial cell lines to viral stimulation Article · 12 Jan 2023
View all (102 more)
- Corrigendum: Type I Interferon Regulates the Survival and Functionality of B Cells in Rainbow Trout Article · 18 Oct 2021
- Pro-Inflammatory and B Cell Regulating Capacities of TWEAK in Rainbow Trout (Oncorhynchus mykiss) Article · 1 Oct 2021
- Characterisation and analysis of IFN-gamma producing cells in rainbow trout Oncorhynchus mykiss Article · Oct 2021
- Immunotoxicity of Xenobiotics in Fish: A Role for the Aryl Hydrocarbon Receptor (AhR)? Article · 31 Aug 2021
- Analysis of immunostimulatory responses and immune tolerance to β-glucans in rainbow trout cell lines Article · Aug 2021
- It's a hard knock life for some: Heterogeneity in infection life history of salmonids influences parasite disease outcomes Article · 21 Jul 2021
- Evaluation of the Potential of Marine Algae Extracts as a Source of Functional Ingredients Using Zebrafish as Animal Model for Aquaculture Article · 29 Jun 2021
- Diversity of Rainbow Trout Blood B Cells Revealed by Single Cell RNA Sequencing Article · 9 Jun 2021
- Individual B cells transcribe multiple rearranged immunoglobulin light chains in teleost fish Article · Jun 2021
- Mechanisms Used by Probiotics to Confer Pathogen Resistance to Teleost Fish Article · 27 Apr 2021
- The Ancient Cytokine BAFF- and APRIL-like Molecule Regulates the Functionality of Teleost IgM+ B Cells Similarly to BAFF and APRIL Article · Apr 2021
- Insights Into the Evolution of the prdm1/Blimp1 Gene Family in Teleost Fish Article · 30 Oct 2020
- Aeromonas salmonicida activates rainbow trout IgM+ B cells signalling through Toll like receptors Article · 8 Oct 2020
- Potential of the Escherichia coli LT(R192G/L211A) toxoid as a mucosal adjuvant for rainbow trout (Oncorhynchus mykiss) Article · Oct 2020
- Distinct modes of action of CD40L and adaptive cytokines IL-2, IL-4/13, IL-10 and IL-21 on rainbow trout IgM+ B cells Article · Oct 2020
- Editorial: Vaccines and Immunostimulants for Finfish Article · 29 Sep 2020
- Passive Immunization Delays Disease Outcome in Gilthead Sea Bream Infected With Enteromyxum leei (Myxozoa), Despite the Moderate Changes in IgM and IgT Repertoire Article · 11 Sep 2020
- First in vivo evidence of pituitary adenylate cyclase-activating polypeptide antiviral activity in teleost Article · Aug 2020
- Rainbow trout mount a robust specific immune response upon anal administration of thymus-independent antigens Article · Aug 2020
- Type I Interferon Regulates the Survival and Functionality of B Cells in Rainbow Trout Article · 9 Jul 2020
- Back From the Brink: Alterations in B and T Cell Responses Modulate Recovery of Rainbow Trout From Chronic Immunopathological Tetracapsuloides bryosalmonae Infection Article · 3 Jun 2020
- A portrait of the immune response to proliferative kidney disease (PKD) in rainbow trout Article · 31 May 2020
- Identificación molecular de Flavobacterium psychrophilum y caracterización de las alteraciones cutáneas en la trucha arcoíris (Oncorhynchus mikyss) procedente de Puno, Perú Article · 4 Feb 2020
- Rainbow Trout IgM+ B Cells Preferentially Respond to Thymus-Independent Antigens but Are Activated by CD40L Article · 17 Dec 2019
- Teleost IgD+IgM− B Cells Mount Clonally Expanded and Mildly Mutated Intestinal IgD Responses in the Absence of Lymphoid Follicles Article · Dec 2019
- Functional nutrition modulates the early immune response against viral haemorrhagic septicaemia virus (VHSV) in rainbow trout Article · Nov 2019
- Identification of CD8α+ dendritic cells in rainbow trout (Oncorhynchus mykiss) intestine Article · Jun 2019
- CpG Oligodeoxynucleotides Modulate Innate and Adaptive Functions of IgM+ B Cells in Rainbow Trout Article · 26 Mar 2019
- Role of teleost B cells in viral immunity Article · Mar 2019
- Local regulation of immune genes in rainbow trout (Oncorhynchus mykiss) naturally infected with Flavobacterium psychrophilum Article · Mar 2019
- Evidence for antimicrobial and anticancer activity of pituitary adenylate cyclase-activating polypeptide (PACAP) from North African catfish (Clarias gariepinus): Its potential use as novel therapeutic agent in fish and humans Article · Mar 2019
- CK11, a Teleost Chemokine with a Potent Antimicrobial Activity Article · 1 Feb 2019
- Different IgM+ B cell subpopulations residing within the peritoneal cavity of vaccinated rainbow trout are differently regulated by BAFF Article · Feb 2019
- Preface to the special issue ‘targeting fish vaccination’ Article · Feb 2019
- Regulation of IgM+ B Cell Activities by Rainbow Trout APRIL Reveals Specific Effects of This Cytokine in Lower Vertebrates Article · 13 Aug 2018
- Identification of the First Teleost CD5 Molecule: Additional Evidence on Phenotypical and Functional Similarities between Fish IgM+ B Cells and Mammalian B1 Cells Article · Jul 2018
- Novel Insights on the Regulation of B Cell Functionality by Members of the Tumor Necrosis Factor Superfamily in Jawed Fish Article · 7 Jun 2018
- Dysregulation of B Cell Activity During Proliferative Kidney Disease in Rainbow Trout Article · 31 May 2018
- Identification of a Potential Common Ancestor for Mammalian Cross-Presenting Dendritic Cells in Teleost Respiratory Surfaces Article · 25 Jan 2018
- Effect of vitamin C on innate immune responses of rainbow trout (Oncorhynchus mykiss) leukocytes Article · Aug 2017
- Expansion and differentiation of IgM+ B cells in the rainbow trout peritoneal cavity in response to different antigens Article · May 2017
- The BAFF / APRIL axis plays an important role in virus-induced peritoneal responses in rainbow trout Article · May 2017
- B Cell-Activating Factor Regulates Different Aspects of B Cell Functionality and Is Produced by a Subset of Splenic B Cells in Teleost Fish Article · 15 Mar 2017
- Attenuated Infectious Hematopoietic Necrosis Virus with Rearranged Gene Order as Potential Vaccine Article · Dec 2016
- T cell immunity in the teleost digestive tract Article · Nov 2016
- Distinct Differentiation Programs Triggered by IL-6 and LPS in Teleost IgM+ B Cells in The Absence of Germinal Centers Article · 2 Aug 2016
- Characterization and expression analysis of chemokine-like receptor 3 gene in rainbow trout Oncorhynchus mykiss Article · 20 Jun 2016
- Exclusion of IgD‐, IgT‐ and IgM‐positive immune cells in Ichthyophonus ‐induced granulomas in rainbow trout Oncorhynchus mykiss (Walbaum) Article · 2 May 2016
- Rainbow trout CK9, a CCL25-like ancient chemokine that attracts and regulates B cells and macrophages, the main antigen presenting cells in fish Article · 17 Mar 2016
- First in-depth analysis of the novel Th2-type cytokines in salmonid fish reveals distinct patterns of expression and modulation but overlapping bioactivities Article · 9 Feb 2016
- Temporary protection of rainbow trout gill epithelial cells from infection with viral haemorrhagic septicaemia virus IVb Article · 5 Feb 2016
- Distribution of T Cells in Rainbow Trout (Oncorhynchus mykiss) Skin and Responsiveness to Viral Infection Article · 25 Jan 2016
- Antiviral Immunity: Origin and Evolution in Vertebrates Book / chapter · 2016
- Adjuvants and Delivery Methods: Current and Novel Book / chapter · 2016
- Teleost Chemokines and Their Receptors Article · 11 Nov 2015
- Effect of temperature and diet on wound healing in Atlantic salmon (Salmo salar L.) Article · 14 Aug 2015
- Transcriptomic and proteomic analyses of splenic immune mechanisms of rainbow trout (Oncorhynchus mykiss) infected by Aeromonas salmonicida subsp. salmonicida Article · Jun 2015
- Early Activation of Teleost B Cells in Response to Rhabdovirus Infection Article · Feb 2015
- Overview of fish immunity Book / chapter · 2015
- Transcriptomic responses in rainbow trout gills upon infection with viral hemorrhagic septicemia virus (VHSV) Article · May 2014
- Modulation of genes related to the recruitment of immune cells in the digestive tract of trout experimentally infected with infectious pancreatic necrosis virus (IPNV) or orally vaccinated Article · May 2014
- Establishment and characterization of a rainbow trout heart endothelial cell line with susceptibility to viral hemorrhagic septicemia virus (VHSV) Article · May 2014
- Adjuvants in Fish Vaccines Other · 7 Mar 2014
- DNA vaccination against a fish rhabdovirus promotes an early chemokine-related recruitment of B cells to the muscle Article · Feb 2014
- Adjuvants and immunostimulants in fish vaccines: Current knowledge and future perspectives Article · Dec 2013
- The Pyloric Caeca Area Is a Major Site for IgM+ and IgT+ B Cell Recruitment in Response to Oral Vaccination in Rainbow Trout Article · 13 Jun 2013
- Molecular characterization of three novel chemokine receptors in rainbow trout (Oncorhynchus mykiss) Article · Feb 2013
- Differential effects of viral hemorrhagic septicaemia virus (VHSV) genotypes IVa and IVb on gill epithelial and spleen macrophage cell lines from rainbow trout (Oncorhynchus mykiss) Article · Feb 2013
- Identification of a novel CCR7 gene in rainbow trout with differential expression in the context of mucosal or systemic infection Article · Oct 2012
- Immune responses elicited in rainbow trout through the administration of infectious pancreatic necrosis virus-like particles Article · Feb 2012
- Chemokines in teleost fish species Article · Dec 2011
- Viral hemorrhagic septicaemia virus (VHSV) up-regulates the cytotoxic activity and the perforin/granzyme pathway in the rainbow trout RTS11 cell line Article · Aug 2011
- Specific Regulation of the Chemokine Response to Viral Hemorrhagic Septicemia Virus at the Entry Site Article · May 2011
- CK12, a rainbow trout chemokine with lymphocyte chemo-attractant capacity associated to mucosal tissues Article · May 2011
- The introduction of multi-copy CpG motifs into an antiviral DNA vaccine strongly up-regulates its immunogenicity in fish Article · Feb 2011
- Differential expression pattern of pituitary adenylate cyclase-activating polypeptide (PACAP) alternative splicing variants and its receptors in the immune system of rainbow trout (Oncorhynchus mykiss) Article · Feb 2011
- Antiviral DNA vaccination in rainbow trout (Oncorhynchus mykiss) affects the immune response in the ovary and partially blocks its capacity to support viral replication in vitro Article · Oct 2010
- Viral hemorrhagic septicemia and infectious pancreatic necrosis viruses replicate differently in rainbow trout gonad and induce different chemokine transcription profiles Article · Jun 2010
- The rainbow trout (Oncorhynchus mykiss) interferon response in the ovary Article · May 2010
- An active DNA vaccine against infectious pancreatic necrosis virus (IPNV) with a different mode of action than fish rhabdovirus DNA vaccines Article · Apr 2010
- Chemokine transcription in rainbow trout (Oncorhynchus mykiss) is differently modulated in response to viral hemorrhagic septicaemia virus (VHSV) or infectious pancreatic necrosis virus (IPNV) Article · Dec 2009
- Immune effects observed after the injection of plasmids coding for rainbow trout (Oncorhynchus mykiss) CK5B, CK6 and CK7A chemokines demonstrate their immunomodulatory capacity and reveal CK6 as a major interferon inducer Article · Oct 2009
- New tools to study RNA interference to fish viruses: Fish cell lines permanently expressing siRNAs targeting the viral polymerase of viral hemorrhagic septicemia virus Article · Jun 2009
- Transcription of immune genes upon challenge with viral hemorrhagic septicemia virus (VHSV) in DNA vaccinated rainbow trout (Oncorhynchus mykiss) Article · Jan 2009
- In vitro search for alternative promoters to the human immediate early cytomegalovirus (IE-CMV) to express the G gene of viral haemorrhagic septicemia virus (VHSV) in fish epithelial cells Article · Dec 2008
- NK-like and oxidative burst activities are the main early cellular innate immune responses activated after virus inoculation in reservoir fish Article · Oct 2008
- Regulation of rainbow trout (Oncorhynchus mykiss) interleukin-8 receptor (IL-8R) gene transcription in response to viral hemorrhagic septicemia virus (VHSV), DNA vaccination and chemokines Article · Sep 2008
- Effects of viral hemorrhagic septicemia virus (VHSV) on the rainbow trout (Oncorhynchus mykiss) monocyte cell line RTS-11 Article · Mar 2008
- Interleukin 8 and CK-6 chemokines specifically attract rainbow trout (Oncorhynchus mykiss) RTS11 monocyte–macrophage cells and have variable effects on their immune functions Article · Jan 2008
- Identification of a Second Group of Type I IFNs in Fish Sheds Light on IFN Evolution in Vertebrates Article · Sep 2007
- In vitro and in vivo differential expression of rainbow trout (Oncorhynchus mykiss) Mx isoforms in response to viral haemorrhagic septicaemia virus (VHSV) G gene, poly I:C and VHSV Article · Jul 2007
- Expression of inducible CC chemokines in rainbow trout (Oncorhynchus mykiss) in response to a viral haemorrhagic septicemia virus (VHSV) DNA vaccine and interleukin 8 Article · 2007
- Co-injection of interleukin 8 with the glycoprotein gene from viral haemorrhagic septicemia virus (VHSV) modulates the cytokine response in rainbow trout (Oncorhynchus mykiss) Article · Jul 2006
- Immunological consequences of the coinfection of brown trout (Salmo trutta) with infectious hematopoietic necrosis virus (IHNV) and infectious pancreatic necrosis virus (IPNV) Article · Jun 2006
- Fish transposons and their potential use in aquaculture Article · Jun 2006
- Expression of genes related to the early immune response in rainbow trout (Oncorhynchus mykiss) after viral haemorrhagic septicemia virus (VHSV) infection Article · Jan 2005
- Conformation- and Fusion-Defective Mutations in the Hypothetical Phospholipid-Binding and Fusion Peptides of Viral Hemorrhagic Septicemia Salmonid Rhabdovirus Protein G Article · Sep 2004
- Characterisation of the syncytia formed by VHS salmonid rhabdovirus G gene transfected cells Article · Jun 2004
- Respiratory burst of turbot (Scophthalmus maximus) macrophages in response to experimental infection with viral haemorrhagic septicaemia virus (VHSV) Article · Nov 2001
- Viral hemorrhagic septicemia virus alters turbot Scophthalmus maximus macrophage nitric oxide production Article · 2001
- Requirements for nitric oxide production by turbot (Scophthalmus maximus) head kidney macrophages Article · Sep 2000
- Rescue of synthetic salmonid rhabdovirus minigenomes Article · 1 Aug 2000
