Ana Rojas
Computational Biology and Bioinformatics (CBBIO.CABD) · CABD
Biography
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Trained as a molecular microbiologist in Madrid and the U.S. (1999), she later specialized in bioinformatics and computational biology, working in several U.S. labs from 1999 to 2003. This includes a NASA-NSCORT fellowship at UCSD in R.F. Doolittle's lab and research in Adam Godzik's lab in La Jolla, CA. Between 2003 and 2006, she continued her work in Spain, holding a Marie Curie fellowship at the CNB-CSIC in the group led by Alfonso Valencia. |
Profile
| Institution | CABD |
| Position | Investigadora Cientifica |
| Home page | http://bioinfocb.es |
| Contact email | a.rojas.m@csic.es |
| ORCID | 0000-0003-0750-9099 |
BCB Hub
| BCB Committee | Outreach |
| BCB Tools | FANTASIA (Functional ANnoTAtion based on embedding space SImilArity) |
| BCB Services |
Research
Research topics
View all (14 more)
Research lines
Projects, networks, transfer & teaching
Research networks
National
- CSIC/BCB.Hub
- CSIC/Life.Hub
- SAB member IGDR, FR.
- SAB president, IMIB, ES.
International
- Desde 2024. ISCB. Track Chair of The Function Community of Interest.
Industry & knowledge transfer
Collaborating companies
- Miembro investigador. TSI-100930-2023-2. Contrato: Cátedra ENIA Google Spain/Universidad de Sevilla en Inteligencia Artificial. 31-08-2024/31-12-2025. IP: Carmen Barroso.
Patents
- Blázquez-Gómez, Jesús, Castañeda-García, Alfredo, Prieto-Márquez Ana I., Rojas-Mendoza, Ana M., Wadel, Simon; Cantillon, Daire; Doherty, A. P201531949. “Cepas de Mycobacterium hipermutables”. España y UK, 31/12/2015. SAS/CSIC/USE
Teaching
Master programs
- MSc in Omics Data Analysis and Systems Biology - Universidad Internacional de Andalucía and Universidad de Sevilla (course "Applications and Discussions in Clinical Medicine", course coordinator; since 2021)
- MSc in Biomedical Research - Universidad de Sevilla (course "Functional Genomics and Biocomputing", external lecturer; since 2016)
- Master in Data Science and Big Data (university-specific degree) - Universidad de Sevilla, Faculty of Mathematics (module "Machine Learning II")
Doctoral programs
- Doctoral Programme in Biotechnology, Engineering and Chemical Technology - Universidad Pablo de Olavide (research line in Engineering, Data Science and Bioinformatics; external lecturer since 2018)
Funded projects 1
Publications 53 entries
- Structural Changes in Gene Ontology Reveal Modular and Complex Representations of Biological Function Article · Jun 2025
- Functional Annotation of Proteomes Using Protein Language Models: A High-Throughput Implementation of the ProtTrans Model Book / chapter · 2025
- MEG8 as an antagonistic pleiotropic mechanism in breast cancer Article · 20 Dec 2024
- Decoding functional proteome information in model organisms using protein language models Article · 2 Jul 2024
- Leveraging Natural Language Processing models to decode the dark proteome across the Animal Tree of Life Preprint · 29 Feb 2024
View all (48 more)
- Identification of novel microRNAs associated with type 2 diabetes by an integrative bioinformatic analysis Article · Dec 2022
- Mutation of SPINOPHILIN (PPP1R9B) found in human tumors promotes the tumorigenic and stemness properties of cells Article · 2021
- Origin and Evolution of Polycyclic Triterpene Synthesis Article · 3 Mar 2020
- VRK1 functional insufficiency due to alterations in protein stability or kinase activity of human VRK1 pathogenic variants implicated in neuromotor syndromes Article · 16 Sep 2019
- Non-canonical dimerization of the androgen receptor and other nuclear receptors: implications for human disease Article · Aug 2019
- Diversity of Quaternary Structures Regulates Nuclear Receptor Activities. Article · Jan 2019
- miARma-Seq, a comprehensive pipeline for the simultaneous study and integration of miRNA and mRNA expression data Software · Jan 2019
- EXD2 governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation. Article · 15 Jan 2018
- RNA sequencing and prediction tools for circular RNAs analysis Book / chapter · 2018
- A non-canonical mismatch repair pathway in prokaryotes Article · 27 Jan 2017
- Dominant‐negative mutation p.Arg324Thr in KCNA1 impairs Kv1.1 channel function in episodic ataxia Article · Aug 2016
- GEMC1 is a critical regulator of multiciliated cell differentiation Article · 1 Mar 2016
- DDRprot: a database of DNA damage response-related proteins Article · 2016
- Type I phosphatidylinositol 4‐phosphate 5‐kinase homo‐ and heterodimerization determines its membrane localization and activity Article · 24 Feb 2015
- Molecular Evolution of Multiple-Level Control of Heme Biosynthesis Pathway in Animal Kingdom Article · 28 Jan 2014
- Emergence and Evolutionary Analysis of the Human DDR Network: Implications in Comparative Genomics and Downstream Analyses Article · 16 Jan 2014
- A common structural scaffold in CTD phosphatases that supports distinct catalytic mechanisms Article · 10 Sep 2013
- Two novel missense mutations in iron transport protein transferrin causing hypochromic microcytic anaemia and haemosiderosis: molecular characterization and structural implications Article · 24 Jul 2013
- A Proteomic Characterization of Factors Enriched at Nascent DNA Molecules Article · Apr 2013
- Uncovering the Molecular Machinery of the Human Spindle-An Integration of Wet and Dry Systems Biology Article · 9 Mar 2012
- The Ras protein superfamily: Evolutionary tree and role of conserved amino acids Article · 23 Jan 2012
- B Lymphocyte Commitment Program Is Driven by the Proto-Oncogene c-myc Article · Jun 2011
- Sumoylation regulates nuclear localization of repressor DREAM Article · May 2011
- An isoform-specific PDZ-binding motif targets type I PIP5 kinase beta to the uropod and controls polarization of neutrophil-like HL60 cells Article · 4 May 2010
- Creating Reference Datasets for Systems Biology Applications Using Text Mining Article · Mar 2009
- A novel patatin-like protein from cotton plant, GhPat1, is co-expressed with GhLox1 during Xanthomonas campestris-mediated hypersensitive cell death Article · 11 Oct 2008
- KCTD5, a putative substrate adaptor for cullin3 ubiquitin ligases Article · 11 Jul 2008
- Exploring the FL-160-CRP gene family through sequence variability of the complement regulatory protein (CRP) expressed by the trypomastigote stage of Trypanosoma cruzi Article · May 2008
- The Nod-Like Receptor (NLR) Family: A Tale of Similarities and Differences Article · 30 Apr 2008
- Are promyelocytic leukaemia protein nuclear bodies a scaffold for caspase-2 programmed cell death? Article · Sep 2007
- Filamin-A regulates actin-dependent clustering of HIV receptors Article · 17 Jun 2007
- The structure of a tandem pair of spectrin repeats of plectin reveals a modular organization of the plakin domain Article · May 2007
- Notch signaling is essential for ventricular chamber development Article · Mar 2007
- Assessment of predictions submitted for the CASP7 function prediction category Article · 2007
- TreeDet: a web server to explore sequence space Article · 1 Jul 2006
- Gas1 is related to the glial cell-derived neurotrophic factor family receptors alpha and regulates Ret signaling Article · May 2006
- A framework for computational and experimental methods: Identifying dimerization residues in CCR chemokine receptors Article · 1 Sep 2005
- Death inducer obliterator protein 1 in the context of DNA regulation - Sequence analyses of distant homologues point to a novel functional role Article · Jul 2005
- Characterization of the protease domain of Rice tungro bacilliform virus responsible for the processing of the capsid protein from the polyprotein Article · 14 Apr 2005
- ACRATA: a novel electron transfer domain associated to apoptosis and cancer Article · 29 Dec 2004
- Erwinia toletana sp. nov., associated with Pseudomonas savastanoi-induced tree knots Article · 1 Nov 2004
- SPOC: A widely distributed domain associated with cancer, apoptosis and transcription Article · 7 Jul 2004
- Quinone biogenesis: Structure and mechanism of PqqC, the final catalyst in the production of pyrroloquinoline quinone Article · 17 May 2004
- Homology modeling provides insights into the binding mode of the PAAD/DAPIN/pyrin domain, a fourth member of the CARD/DD/DED domain family Article · Sep 2003
- Comparative analysis of apoptosis and inflammation genes of mice and humans Article · Jun 2003
- Incidence of salmonellae in captive and wild free-living raptorial birds in central Spain Article · 22 Jan 2003
- The occurrence of type S1A serine proteases in sponge and jellyfish Article · 1 Dec 2002
- gyrA mutations associated with nalidixic acid-resistant salmonellae from wild birds Article · Sep 2002
