David Juan Sopeña
Biography
|
Principal Investigator - Functional and Comparative Multi-Omics. Spanish National Centre for Biotechnology (CNB-CSIC). Tenured Scientist at the CNB-CSIC since January 2024. (Description curated from publicly available data.) |
Profile
| Institution | CNB |
| Position | Tenured Scientist |
| Home page | https://www.linkedin.com/in/david-juan-8769364/ |
| Contact email | david.juan@upf.edu |
| ORCID | 0000-0003-1912-9667 |
Research
Research topics
GenomicsProtein-Protein InteractionsComparative Genomics
Research lines
Publications 74 entries
- Convergent Amino-Acid Substitutions Link Primate Longevity to Male-Fertility Genes Preprint · 10 Sep 2026
- Detection of Specificity-Determining Positions in Protein Families Book / chapter · 1 Nov 2025
- Phylogenetic Signal in Primate Tooth Enamel Proteins and its Relevance for Paleoproteomics Article · 21 Jan 2025
- Mapping recurrent mosaic copy number variation in human neurons Article · 17 May 2024
- Vocal learning–associated convergent evolution in mammalian proteins and regulatory elements Article · 29 Mar 2024
View all (69 more)
- Identification of constrained sequence elements across 239 primate genomes Article · 29 Nov 2023
- Genomic data resources of the Brain Somatic Mosaicism Network for neuropsychiatric diseases Article · 20 Nov 2023
- CAAStools: a toolbox to identify and test Convergent Amino Acid Substitutions Article · 1 Oct 2023
- Author Correction: Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia Article · 30 Aug 2023
- Author Correction: The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing Article · 29 Aug 2023
- Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions Article · Aug 2023
- Ghost admixture in eastern gorillas Article · 27 Jul 2023
- Y chromosome sequence and epigenomic reconstruction across human populations Article · 9 Jun 2023
- The landscape of tolerated genetic variation in humans and primates Article · 2 Jun 2023
- A global catalog of whole-genome diversity from 233 primate species Article · 2 Jun 2023
- Three-dimensional genome rewiring in loci with human accelerated regions Article · 28 Apr 2023
- The functional and evolutionary impacts of human-specific deletions in conserved elements Article · 28 Apr 2023
- The contribution of historical processes to contemporary extinction risk in placental mammals Article · 28 Apr 2023
- Relating enhancer genetic variation across mammals to complex phenotypes using machine learning Article · 28 Apr 2023
- Mammalian evolution of human cis-regulatory elements and transcription factor binding sites Article · 28 Apr 2023
- Leveraging base-pair mammalian constraint to understand genetic variation and human disease Article · 28 Apr 2023
- Integrating gene annotation with orthology inference at scale Article · 28 Apr 2023
- Insights into mammalian TE diversity through the curation of 248 genome assemblies Article · 28 Apr 2023
- Evolutionary constraint and innovation across hundreds of placental mammals Article · 28 Apr 2023
- Comparative genomics of Balto, a famous historic dog, captures lost diversity of 1920s sled dogs Article · 28 Apr 2023
- Comprehensive multi-omic profiling of somatic mutations in malformations of cortical development Article · 12 Jan 2023
- Current advances in primate genomics: novel approaches for understanding evolution and disease Article · 4 Jan 2023
- Control-independent mosaic single nucleotide variant detection with DeepMosaic Article · 2 Jan 2023
- The population genomic legacy of the second plague pandemic Article · Nov 2022
- Transcriptome innovations in primates revealed by single-molecule long-read sequencing Article · 15 Jul 2022
- Somatic Mutations Detected in Parkinson Disease Could Affect Genes With a Role in Synaptic and Neuronal Processes Article · 28 Apr 2022
- Somatic mosaicism reveals clonal distributions of neocortical development Article · 20 Apr 2022
- Evolutionary analysis of gene ages across TADs associates chromatin topology with whole genome duplications Preprint · 11 Jun 2021
- Epigenomic profiling of primate lymphoblastoid cell lines reveals the evolutionary patterns of epigenetic activities in gene regulatory architectures Article · 25 May 2021
- Copy number variation underlies complex phenotypes in domestic dog breeds and other canids Article · 16 Apr 2021
- Variation in predicted COVID‐19 risk among lemurs and lorises Article · Apr 2021
- Comprehensive identification of somatic nucleotide variants in human brain tissue Article · 29 Mar 2021
- The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing Article · 11 Jan 2021
- Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia Article · 11 Jan 2021
- A comparative genomics multitool for scientific discovery and conservation Article · 11 Nov 2020
- Expanding the Geographic Characterisation of Epstein–Barr Virus Variation through Gene-Based Approaches Article · 29 Oct 2020
- Somatic mutations in Parkinson disease are enriched in synaptic and neuronal processes Preprint · 15 Sep 2020
- Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships Article · 5 Jun 2020
- Extreme differences between human germline and tumor mutation densities are driven by ancestral human-specific deviations Article · 19 May 2020
- Copy number variants and fixed duplications among 198 rhesus macaques (Macaca mulatta) Article · 11 May 2020
- Reconstructing Denisovan Anatomy Using DNA Methylation Maps Article · Feb 2020
- Mutation distribution density in tumors reconstructs human’s lost diversity Preprint · 19 Sep 2019
- Selective single molecule sequencing and assembly of a human Y chromosome of African origin Article · 2 Jan 2019
- Spatiotemporal transcriptomic divergence across human and macaque brain development Article · 14 Dec 2018
- Loose ends: almost one in five human genes still have unresolved coding status Article · 5 Nov 2018
- Unveiling the molecular basis of disease co-occurrence: towards personalized comorbidity profiles Preprint · 30 Sep 2018
- Loose ends: almost one in five human genes still have unresolved coding status Article · 30 Jun 2018
- Intronic CNVs cause gene expression variation in human populations Preprint · 1 Aug 2017
- Conservation of coevolving protein interfaces bridges prokaryote–eukaryote homologies in the twilight zone Article · 13 Dec 2016
- Detection of significant protein coevolution Software · 24 Feb 2015
- Multiple evidence strands suggest that there may be as few as 19 000 human protein-coding genes Article · 16 Jun 2014
- Emerging methods in protein co-evolution Article · 5 Mar 2013
- Differential Immune-Reactivity and Subcellular Distribution Reveal the Multifunctional Character of Profilin in Pollen as Major Effect of Sequences Polymorphism Book / chapter · 14 Nov 2012
- Incorporating information on predicted solvent accessibility to the co-evolution-based study of protein interactions Article · 10 Oct 2012
- Mirroring co-evolving trees in the light of their topologies Article · 6 Mar 2012
- JDet: interactive calculation and visualization of function-related conservation patterns in multiple sequence alignments and structures Article · 9 Dec 2011
- Selection of organisms for the co-evolution-based study of protein interactions Article · 12 Sep 2011
- Identification of a MicroRNA Panel for Clear-cell Kidney Cancer Article · Apr 2010
- Protein interactions and ligand binding: From protein subfamilies to functional specificity Article · 19 Jan 2010
- Co‐evolution and co‐adaptation in protein networks Article · 20 Feb 2008
- Enhancing the prediction of protein pairings between interacting families using orthology information Article · 23 Jan 2008
- High-confidence prediction of global interactomes based on genome-wide coevolutionary networks Article · 22 Jan 2008
- Protein-protein interactions: analysis and prediction Book / chapter · 2008
- TSEMA: interactive prediction of protein pairings between interacting families Article · 1 Jul 2006
- Assessing Protein Co-evolution in the Context of the Tree of Life Assists in the Prediction of the Interactome Article · Sep 2005
- Accessible Protein Interaction Data for Network Modeling. Structure of the Information and Available Repositories Book / chapter · 2005
- Computational methods for the prediction of protein interaction partners Other · 15 Oct 2004
- Identification of amino acid residues crucial for chemokine receptor dimerization Article · 11 Jan 2004
- A neural network approach to evaluate fold recognition results Article · 6 Feb 2003